Dr. Shao-Gui WU (伍绍贵博士）
College of Chemistry and Materials Science,Sichuan Normal University 
Abstract: In this work, we use simple coarse grained models so as to explain some important problems in biological membrane system, such as vesicle formation, vesicle fusion, vesicle fission and so on. In particular, a mesoscopic dissipative particle dynamics (DPD) simulation method is used to probe the mechanism of protein-mediated membrane fusion. The coarse-grained models for proteins are designed based on the function of fusion proteins. Attractive forces have been introduced to produce a protein complex. The formation of protein complexes provides mechanical forces to bring membranes in proximity and trigger their merging. We believe that our simulation studies may shed light on the general principles of this type of biological system.

Location: 606 Conference Room, No.3 Heqing Road, Haidian District, Beijing Computational Science Research Center 
Date&Time: Jan. 6, 2012 (Friday)  10:00-11:00 a.m.