The concept of chirality, characterized by the geometric asymmetry between mirror images, has penetrated into a wide spectrum of modern science, from the structure of universe (e.g. spiral galaxy) to the dynamics of elementary particle (e.g. helicity of massless Weyl fermion). In condensed matter physics, crystal chirality can induce unusual motion of electrons, which leads to orbital- and spin- momentum lockings, nonreciprocal magnetoresistances, and circularly polarized luminescence etc. On the other hand, the geometric (Berry) phase has become a very important tool to understand various effects in condensed matter physics including (quantized) anomalous Hall effect, topological materials, and electric charge polarization in crystalline solids. In this talk, I will introduce our recent works about chirality-driven phenomena based on the concept of geometric phase.